The scuffling New York Mets play host to the Tampa Bay Rays, as the pair open a three-game interleague series Friday night at Citi Field.
The Tampa Bay Rays and Houston Astros are set to start a four-game series on Thursday night, when they collide at Tropicana Field.
The Tampa Bay Rays and New York Yankees are set to start a three-game series at Tropicana Field on Friday night.
The American League East will square off with the American League West, when the Tampa Bay Rays begin a three-game series against the Astros on Monday.
Less than a week after they faced one another in Seattle, the Mariners are in St. Petersburg where they are set to start a four-game series against the Tampa Bay Rays, starting Thursday night.